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Indicated for the symptomatic treatment of respiratory diseases associated with an impairment or elimination of the mucusafscheiding: - Acute bronchitis, tracheobronchitis, chronic bronchitis - chronic obstructive bronchopulmonary disease, bronchiectasis - acute sinusitis, chronic sinusitis.
Qualitative and quantitative composition:
Bisolvon 8 mg tablets: one tablet contains 8 mg broomhexinehydrochloride.
Bisolvon 8 mg / 5 ml syrup: 5 ml syrup contains 8 mg broomhexinehydrochloride.
Bisolvon 0.2% oral drops, solution: 1 ml solution containing 2 mg broomhexinehydrochloride.
For excipients, see List of excipients.
Oral drops, solution.
Posology and method of administration:
Oral use: to 8 mg tablets, syrup or 8 mg / 5 ml oral drops use - solution to 2 mg / 1 ml (1 ml = 14 to 15 drops).
Adults and children over 10 years.
3 x per days, 8 to 16 mg = 1 to 2 tablets or syrup, or 1 or 2 mates 4 to 8 ml solution.
Children 5 to 10 years.
3 x per day, 8 mg = 1 tablet or syrup 1 scoop or 4 ml solution.
Children from 2 to 5 years.
2 to 3 times a day, 1 / 2 to 1 scoop syrup or 2 to 4 ml solution, depending on body weight (0.75 mg/kg/24 h).
Infants and children up to 2 years.
3 times a day, about 2 drops of solution / kg (0.75 mg/kg/24 h).
In adults is the maximum dose of 32 mg / dose, maximum daily dose is 96 mg.
This is a medicine, no prolonged use without medical advice, keep away from children, read the leaflet carefully. Ask your doctor or pharmacist. In case of side effects, contact your doctor.
Hypersensitivity to bromhexine or any of the other ingredients of the medicine.
Special warnings and precautions for use:
Bisolvon oral drops, solution (which has an acidic pH): the acidity of the solution is necessary to caution ulcuspatiënten.
If the patient can not cough up sputum, the airway, if necessary, be kept by postural drainage or aspiration.
Association of a drug that promotes sputum with a hoeststillend means illogical.
Pregnancy and lactation:
bromhexine was already a large number of pregnant women and women of childbearing age used. It was never any toxic effects on the mother or the fetus determined.
Nevertheless, one also with this product, as with all medicines, the usual precautions, especially during the first 3 months pregnancy.
bromhexine can penetrate into the breast milk and is not recommended during lactation.
Sometimes mild gastrointestinal disturbances occur including nausea, dyspepsia, vomiting, diarrhea, dizziness and headache. Very rarely allergic reactions were observed, mainly skin rash, bronchospasm, angioneurotic edema and anaphylactic reactions. Exceptional increases were reported transaminases.
Effects on ability to drive and use machines:
Bisolvon The therapeutic margin is very large, single doses of the order of 50 times the therapeutic dose would be likely to cause hypotension.
In overdose symptomatic treatment should be administered.
List of excipients:
Tablet: Lactose - Maize starch - gelatin - Magnesium.
Syrup : Tartaric acid - Hydroxyethylcellulose -- sorbitol solution - Glycerol - Menthol - Cherry Flavor - Cocoa aroma - Ethanol (anhydrous) - benzoic acid - purified water.
Oral drops, solution : Tartaric Acid - Methyl - Purified water.
Interaction with other medicinal products and other forms of interaction:
Concomitant administration of bromhexine and antibiotics (amoxicillin, cefuroxime, erythromycin, doxycycline) may lead to increased antibiotic concentration in the lungs .
No other clinically significant interaction was reported.
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