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The present antiseptics are not sterilizing, they temporarily reduce the number micro-organisms.
These forms serve as an aid in the initial treatment of skin diseases caused by bacteria or of potential dermatological surinfecties.
It can serve as an antiseptic on skin and mucosa. It is this used in surgery and traumatology, in the gynécologie and stomatology.
Since the solution is not working fast enough, is not suitable for disinfection before a puncture or before an injection.
As an aid in the initial treatment of skin diseases caused by bacteria or of potential dermatological surinfecties staphylococci-like folliculitis and perionyxis by pus-forming cocci.
Symptomatic treatment of painful diseases of the mouth, throat and especially as an aid in the treatment of pharyngitis, mouth ulcers and in the treatment of surgery on the tonsils.
Qualitative and quantitative composition:
Hexamidini di-isoaethionas 100 mg - Alcohol isopropylicus - Aqua qs purificata ad 100 ml.
Hexamidini di-isoaethionas 100 mg - 50 mg Tetracaïni hydrochloridum - Acidum aceticum - Sodium acetas - Glycerinum - Aethanolum - Menthae piperitae aetheroleum - Saccharum - Aqua qs purificata ad 100 g.
Hexamidini di-isoaethionas 150 mg - Propylenglycolum - Dimethoxymethane. crudum - Alcohol isopropylicus - poly ethyl glycol ether. - Aqua purificata q.s. ad 100 ml.
Hexomedine solution: solution for cutaneous application.
Hexomedine collutorium: oromucosal spray for use.
Hexomedine transcutaan solution for cutaneous application to 1.5?.
Posology and method of administration:
dilute to use 2 to 3 times daily, or just topical application, either in the form of a saturated connection, either locally bathing.
The solution can also be one or several times a day, possibly after dilution, are sprayed using a compressed air or oxygen injector .
Rinsing is not necessary.
for the disinfection of a ground operation, the Hexomedine solution extemporaan be colored with methylene blue. This means do not change the activity of the product.
24 hours 6 short term sprays (each spray is to Fri 0.20 ml solution, corresponding with 0.2 mg hexamidine).
If after 3 to 4 days no improvement is found with this drug, it is advisable to consult a physician.
instrijkmiddel or twice daily as a bath room.
For nail and nageldbedinfecties can Hexomedine transcutaan used - either in the form of a wet dressing for 30 to 45 minutes - Either to bathe for 1 to 3 min
Hexomedine transcutaan The bottle also has a wide neck opening for the use of a finger nail infection in the fluid to stabbing. Rinse afterwards is not necessary.
Not use on open wounds or mucosa, even under occlusion.
This is a medicine, no prolonged use without medical advice, keep away from children, read the leaflet carefully. Ask your doctor or pharmacist. In case of side effects, contact your doctor.
Known hypersensitivity to diamidine derivatives (or constituent components).
The preparations are not appropriate for disinfection for a puncture or an injection, because they do not work fast enough. They are also not suitable for the disinfection of surgical equipment.
Known hypersensitivity to tetracaine or related products. Do not use in children younger than 6 years given the verslikkingsgevaar.
Special warnings and precautions for use:
Although in animal experiments the systemic symptoms of low hexamidine were pronounced, the threat of humans is not completely excluded.
Is particularly fear of systemic effects such as the antiseptic is used repeatedly over a large area, under occlusion, in a breach (for burned) skin, mucosa, the skin of an infant or a premature (because the ratio of body surface area / weight and the occlusive effect of diapers at the height of the bounce). Avoid contact with eyes.
not use on open wounds and mucosa.
For choking by anesthesia of the oropharynx: - no use for meals or taking a drink - caution is advised when using this drug in children younger than 12 years.
The indication shall not justify a treatment duration of more than 5 days, the more it can cause an imbalance in the oral microbial flora at risk of bacterial or fungal dissemination.
a repeated or prolonged treatment at the level of the mucosa increases the risk of systemic toxic effects of contacta aesthetics (disease of the central nervous system with seizures, depression of the cardiovascular system).
Pregnancy and lactation:
Hexomedine solution transcutaan.
Given the weak absorption of hexamidine, these products may be used during pregnancy and lactation .
In the absence of concrete data and the risk of a high absorption of tetracaine, the use of this drug is not recommended during pregnancy and lactation.
To date there have been no reports of systemic side effects in humans.
sensitization may occur by hexamidine. The frequency varies depending on the dosage form and degree of degradation epiderm. The water-alcohol solution, frequently used on an eroded or breached skin is more liable than other dosage forms.
Contact dermatitis due to hexamidine has some details that evoke the phenomenon of Arthus and to suggest that humoral immunological mechanisms involved.
Clinically there is usually a difference with the classic contact eczema, there are usually infiltration of the rash, which occur as a half crescent-shaped, single or grouped vesicles maculopapular. At the place where the antiseptic was applied to them before they multiply and flow together, since they survive for more isolated. These lesions often disappear slowly.
Benign local intolerance symptoms can be observed: stimulation of feeling, itching, burning and skin dryness. They rarely cause discontinuation of treatment.
Tetracaine may also cause skin sensitization.
General disorders and administration site.
hexamidine or sensitization to tetracaine (collutorium ) with risk of anaphylactic reactions.
For collutorium: tetracaine is transient immunity of the tongue and ability to cause choking (see also 'special precautions').
Effects on ability to drive and use machines:
Hexomedine is unlikely to influence the ability to drive and operate machinery.
To date no cases of overdose reported.
In the event that excessive doses used, its systemic effects of the antiseptic or anesthetic (for collutorium) can not (see also 'special precautions').
Hexomedine and transcutaan solution containing isopropanol.
If the product is accidentally swallowed, it is recommended to administer activated charcoal and gastric lavage may apply, in If the victim exhibits a decreased breathing, as soon as possible should be transferred to a hospital.
Treatment of overdose by tetracaine.
Symptomatic treatment: preservation of the circulatory, respiratory and monitoring of convulsions (diazepam and phenobarbital or by IV route).
List of excipients:
See section 'Qualitative and quantitative composition.
Interaction with other medicinal products and other forms of interaction:
Given potential interactions (antagonism, inactivation,...) is consecutive or simultaneous use of different antiseptics to avoid.
Hexomedine not mix with other antiseptics due to risk of inactivation of the antiseptic.
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