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The symptomatic treatment of acute and chronic diarrhea of various origins.
Imodium is recommended for travelers' diarrhea (turista) . This indication is treatment of 2 days is sufficient. Only with fever and blood in the stool suggests they prefer to use the causal germ is known.
After ileostomy may Imodium fewer the number of bowel movements, less bulky and more bound to make.
Capsules. 2 mg
loperamidehydrochloride (R 18 553) per capsule.
Other ingredients: lactose, maize starch, talc, magnesium stearate.
The capsule shell contains yellow and black iron oxide (E172), indigo carmine (E132), erythrosine (E 127), titanium oxide and gelatin.
0.2 mg loperamidehydrochloride (R 18 553) per ml of drinkable liquid.
Other ingredients: ethanol 0.073 mg / ml, glycerine, sodium, COCHINEAL A RED (E 124), methyl, propyl, citric acid, raspberry aroma, currants aroma, water.
Instant melt tablets.
2 mg loperamide hydrochloride (R 18 553) per tablet.
Other ingredients: gelatin, mannitol, aspartame, mint flavor, sodium .
Posology and method of use:
Imodium no initial therapy for severe diarrhea associated with fluid and electrolyte loss. More specifically in infants and children, preference will be given to compensate this loss through parenteral or oral route.
Adults and children over 6 years (capsules, drinks, instant melt tablets):
Acute Diarrhea: The starting dose is 2 capsules, 2 or 4 doseerdoppen instant melting tablets for adults and 1 capsule, 1 or 2 doseerdoppen instant melt tablets for children. Then 1 capsule, 1 or 2 doseerdoppen instant melt tablet after each subsequent loose stool.
Chronic diarrhea and anal incontinence: The starting dose is 2 capsules, 2 or 4 doseerdoppen instant melt tablets per day for adults and 1 capsule, 1 or 2 doseerdoppen instant melt tablets per day for children. That dose is adjusted until 1 or 2 formed bowel movements per day occur, what gewoonlijkbereiktmet a maintenance dose of 1 to 6 capsules, 1 to 6 instant melt tablets or 2 to 12 days per doseerdoppen.
Both acute and chronic diarrhea in adults, the total dose of 8 capsules, 8 or 16 doseerdoppen instant melt tablets per day limit. In children, the maximum daily dose of 3 capsules, 3 or 6 doseerdoppen instant melt tablets per 20 kg body weight. It should also be to ensure that you never exceed 8 capsules, 8 instant melt tablets or 16 days per doseerdoppen administer.
Children 2 to 6 years (drink). Dispensing closures
1 (= 5 ml) per 10 kg body weight after each loose stool, 2 to 3 times per day. The maximum daily dose is 3 doseerdoppen per 10 kg body weight.
The bottle of liquor should be opened as follows: push the plastic screw cap down while at the hands of the clock running (see Figure).
Once the bowel is faster or more than 12 hours if no bowel movement occurs, one administration stop.
Instructions for the instant melting tablets:
Imodium instant melt tablets are available in blisters of 10 tablets. One pack contains 2 or 6 blisters. Trade following the tablets from the blister to incorporate
1.) Pull the edge of the film up.
2.) Pull the foil completely.
3.) gently push the tablet up, (without touching the tablet).
4.) Remove the tablet from the blister.
Since the instant melt tablets are fragile, they can not be pushed through the foil. This would pulverize the tablet. The instant melting tablet is placed on the tongue, naturally melts away and is swallowed with the saliva. There should be no liquid taken.
This is a medicine, no prolonged use without medical advice, keep away from children, read the leaflet carefully. Ask your doctor or pharmacist. In case of side effects, contact your doctor.
Imodium should not be used: - in children under 2 years.
Imodium instant melt tablets are not suitable for children younger than 6 years. With known hypersensitivity to any ingredient of Imodium. In all cases where the intestinal peristalsis should not be suppressed (eg subobstructie). The administration of Imodium will immediately be discontinued if there constipation, abdominal distension or signs of subileus occur. When the liver is required for metabolizing the drug, is deficient, so a relative overdose could occur. In patients with acute ulcerative colitis or pseudo-membranous colitis associated with administration of broad-spectrum antibiotics. The primary treatment of acute dysentery, characterized by the presence of blood in the stool and high fever.
Given only symptomatic treatment is Imodium, diarrhea must first be treated causally, whenever causal treatment available.
Imodium out of reach of children and should be kept to children younger than 6 years are given without prescription or medical supervision.
Patients with diarrhea, and particularly in children, the diarrhea to a lack of fluid and electrolytes lead. In such cases the administration of fluid and electrolytes the most important measure.
If no clinical improvement in acute diarrhea is diagnosed within 48 hours, the administration of Imodium to stop and put the patient is advised to contact the treating doctor.
of patients with acute ulcerative colitis should run against caution. Drugs that prolong the transit time, when some of them may give rise to a toxic megacolon.
Patients with hepatic dysfunction are the most closely monitored for signs of CNS toxicity due to the important role of the liver in the metabolism of loperamide (first pass).
Since loperamide geëxcreteerd not the urine, dosage adjustment in patients with renal impairment probably not necessary.
patients with phenylketonuria should be taken into account that one instant Imodium melting tablet containing 0.75 mg aspartame, equivalent to 0.42 mg phenylalanine.
Pregnancy and lactation:
Although there is no evidence that Imodium teratogenic or embryotoxic properties might have therapeutic benefits must be weighed against the potential risks before taking Imodium to administration during pregnancy, especially during the first trimester.
Given the enterohepatic circulation of Imodium, the group in breast milk can be found, very small. But it is advised not to use Imodium during the lactation period.
The following adverse effects were reported: - Hypersensitivity reactions such as rash, urticaria and very rare cases of anaphylactic shock and blistering skin rash with such Toxic epidermal necrolysis. In most of these cases the patients took other drugs that these phenomena may have caused or contributed to that effect. - Constipation and / or abdominal distension, in extremely rare cases associated with ileus, especially in cases where the prescription information was not respected (see sections 'Posology and method of use' and 'Contra-indications') - Urinary retention was reported only rarely - A number of complaints which are difficult to distinguish from the typical symptoms associated with various forms of diarrhea, including: - abdominal pain or discomfort - nausea and vomiting - fatigue - drowsiness or dizziness - dry mouth.
In the instant taking Imodium tablets melt some patients complained of a burning or tingling sensation on the tongue, immediately after use.
Driving use of vehicles and machines:
fatigue, dizziness or drowsiness may occur (see 'Undesirable effects'), then it is advisable not to drive or operate machinery.
In animal studies demonstrated that the acute toxic dose 102 times higher than the minimum dose needed for an effect on the diarrhea for 8 hours.
Children, whose blood-brain barrier is not functioning properly, can facilitate depression of the central nervous system development than adults. In case of overdosage (including relative overdose due to hepatic insufficiency), a depression of the central nervous system action. The symptoms that you may encounter are: miosis, muscular hypertonia, stupor, coordination disturbances, drowsiness and respiratory depression. Urinary retention and an overdose can ileusachtig syndrome. The specific antidote is naloxone. Since the duration of Imodium is longer than that of naloxone (1 to 3 hours), may be necessary to administer naloxone repeatedly. Therefore patients should be closely monitored for at least 48 hours, so that any depression of the central nervous system can be established.
For children, the naloxondosis 0.01 mg / kg, with a maximum total dose of 10 mg. If no result is achieved, it is not a morfinomimetisch effect. Furthermore, it could perform a gastric lavage with aqueous potassium permanganate (20 mg/100 ml), possibly followed by a cathartic (eg 30 g sodium sulphate in 250 ml water).
were reported interactions with drugs with similar pharmacological properties. In children with drug combinations that have a central depressing effect, be avoided.
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