Reduced price! Panadol 500mg 20 tabl

Panadol 500mg 20 tabl

0.17 kg

GLAXOSMITHKLINE CONS. HEALTHCARE

0056481

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Therapeutic Indications:

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3,15€

3,50€

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Panadol 500mg 20 tabl

.

Therapeutic Indications:

Symptomatic treatment of fever and pain.

Qualitative and quantitative composition:


Panadol 500 mg tablets.

Paracetamol 500 mg. For excipients, see section 'List of excipients.
Panadol 1 g tablets.

Paracetamol 1 g For excipients, see section 'List of excipients.

Pharmaceutical form:


Panadol tablets 500 mg:
tablets.
Panadol tablets 1 g:
tablets.

Posology and method of administration:


Panadol 500 mg tablets.
Adult
: 1 to 2 tablets up to 3 times a day.
Children 12 years and over:
to 1 tablet 3 times a day.
Children from 6 to 12 years
: 1 / 2 to 1 tablet up to 3 times a day.
Panadol 1 g tablets.
Adults
: 1 / 2 to 1 tablet up to 3 times a day.
Children 12 years and over
: 1 / 2 tablet up to 3 times per day .
For children the usual dose is 30 to 40 mg / kg per 24 hours. The maximum dose is 15 mg / kg / dose and 60 mg / kg per 24 hours.
The interval between two intakes should amount to at least 4 hours.
The duration of treatment should be as short as possible and, the period when symptoms are present not to exceed.
patients with impaired liver function the dose should be lower.
in elderly persons, no dosage adjustment is necessary.

This is a medicine, no prolonged use without medical advice, keep away from children, read the leaflet carefully. Ask your doctor or pharmacist. In case of side effects, contact your doctor.

Contraindications:


Hypersensitivity to paracetamol, phenacetin or any of the excipients.
Severe hepatic impairment.
Renal.
Repeated administration of paracetamol is contraindicated in patients suffering from anemia or cardiac or pulmonary disease.

Special warnings and precautions for use:


The risk of hepatotoxicity may be increased in patients taking enzyme inducers such as barbiturates and anticonvulsants used.
Excessive use of alcohol should be avoided during treatment with Panadol for the chance to reduce a possible hepatotoxicity.
Caution is advised in patients with hepatic impairment.
in elderly persons liver and renal function tests should be performed at any time a liver or renal failure to detect.
The duration of treatment should be as short as possible and limited to the period when symptoms are present. It is not completely excluded paracetamol plays a role in the development of certain nefropathieën caused by analgesics.

Pregnancy and lactation:


Paracetamol crosses the placenta and is excreted in breast milk. Panadol is prudently advised not to use in the first trimester of pregnancy. In very rare cases there have been reports of an allergic reaction to infant acetaminophen, which was issued through breast milk.

Side effects:


Platelet, bleeding and coagulation.

Rare cases of thrombocytopenia, leukopenia and hemolytic anemia are reported.
Skin and subcutaneous tissue.

Rare cases of skin reactions including erythema, urticaria, angioneurotic edema and other signs of anaphylaxis have been reported.
Disorders of the liver.

Biological signs of hepatotoxicity, comprising an increase of transaminases were observed after treatment with high doses. This is reinforced by alcohol hepatotoxicity and microsomal leverinductoren (see 'Interactions').
If such reactions occur, treatment should be discontinued.

Effects on ability to drive and use machines:


Acetaminophen has no effect on the ability to drive and use machines.

Overdose:


In the adult, a single dose of 8 to 10 g cause hepatic necrosis. In children, the toxic dose is 120 mg / kg. The toxic dose is lower in patients with hepatic insufficiency and chronic alcoholism.
The symptoms (pallor, nausea, vomiting) usually manifest themselves within the first 12 to 24 hours, hepatic manifests only occur 3 days after the overdose . Hospitalization is required, even in cases of suspected intoxication. Poison Control Center can be contacted on the number 070/245.245.
Treatment.

When a patient by the oral route has taken a paracetamol overdose, the stomach should be emptied as soon as possible by means of a gastric lavage or induce vomiting. An overdose via rectal route is unlikely.
One can start treatment with administration of activated charcoal, but the most important therapeutic measure is still the intravenous administration of N-acetylcysteine, at a rate of 150 mg / kg in 30 à 60 minutes, then 50 mg / kg in 4 hours and then 100 mg / kg in 16 hours. The volume of 5% glucose solution used as infusion fluid should be determined by the age and weight of the patient.
In case of very serious overdose, administration of N-acetylcysteine continue until the 48 e hours.

List of excipients:


Panadol 500 mg tablets.
Tablet core:
Liquid cornstarch - Maize -- Talk - stearic acid - povidone - Potassium sorbate.
Tablet
: Hypromellose - Triacetin.
Panadol 1 g tablets.
Kern of the tablet:
Liquid starch - Starch - Talk - stearic acid - povidone - Potassium sorbate.
Tablet:
Hypromellose - Triacetin.

Interaction with other medicinal products and other forms of interaction:


The administration of activated charcoal reduces the absorption of paracetamol in cases of overdose.
Leverenzyminductoren (such as barbiturates, diphantoïne) and alcohol may enhance the hepatotoxicity of paracetamol.
The half-life of chloramphenicol may be extended from 2 to 3 hours to 18 to 24 hours in case of simultaneous intake of paracetamol.
Acetaminophen may interfere with the effect of warfarin.
The weak binding of paracetamol to plasma proteins may be used concomitantly with anticoagulants. However, intake of paracetamol for several days may increase the risk of bleeding. In that case, a regular monitoring of the International Normalized Ratio (INR) is recommended.
Given the risk of a decline in the number of leukocytes (leukopenia) with concomitant intake of paracetamol and AZT (zidovudine), should concomitant use only under medical supervision available.
The absorption of paracetamol may increase when used concomitantly with metoclopramide and drop when it is used concurrently with cholestyramine.
Concomitant intake of diflunisal increases the serum concentration of paracetamol. Elevated serum concentrations are associated with hepatotoxicity.

Incompatibilities:


Not applicable.

 

Delivery form Tablets
Brands Panadol
Type of product Medicine

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