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Syngel is indicated in the symptomatic treatment of gastritis. It exerts a force in the symptomatic reflux oesophagitis-related (ie that due to a hiatus hernia).
One teaspoon (5 ml) contains:
Active ingredients: Magnes. carbon. and aluminin. hydroxide. cum praecipit. (codried gel) 125 mg - Magnes. hydroxide. 200 mg - Magnes. trisilicas 125 mg - Lidocaïni hydrochlorid. 12.5 mg.
Non-active substances: - chlorhexidine. diacet - hydroxyethylcellulose. - Sodium saccharin. - Sorbitol. - Anethole. - Aethanol. - Aqua. purificata.
Posology and method of use:
Vial: shake the bottle well before use.
Symptomatic gastritis .
One to two teaspoonfuls (5 ml / spoon) FOR the three meals and at bedtime. This is the usual dosage.
Esophagitis by reflux.
One to two teaspoonfuls (5 ml / spoon) IMMEDIATELY AFTER the meal and at bedtime . Higher doses can be given if the clinical symptoms require.
Patients with renal insufficiency.
A reduction of the dose or frequency of administration may prove necessary (see section ' special precautions ').
Syngel was not tested in children.
This is a drug, not prolonged use without medical advice, keep away from children, read the leaflet carefully. Ask your doctor or pharmacist. In case of side effects, contact your doctor.
Achalasia, paralytic ileus, intestinal obstruction. Intolerance to lidocaine or local anesthetic agents belonging to the family of amides or other components. Severe renal impairment.
Digestive disorders should always be a thorough etiological be examined. The use of Syngel, the symptoms of a neoplastic lesions mask if this is not systematically searched. Caution is advised in patients with renal insufficiency and in patients with chronic hemodialysis treatment by antacids. The presence of severe cirrhosis requires special supervision.
Pregnancy and lactation:
For reasons of absorption disorders of phosphorus, fluorine and iron, and the unknown effects of lidocaine on the embryological development (although limited is absorbed) is prescribing this drug during pregnancy and lactation is not recommended.
Magnesium carbonate exerts a moderate laxative effect of light by stimulating the intestinal mucosa. In patients with severe renal insufficiency may occur that a magnesium retention cardiovascular and neuromuscular disorders can cause.
Aluminum antagoniseert the above-mentioned substance by its clogging and absorbing properties. When it is taken separately may provoke nausea and vomiting. The intestines can insoluble aluminum phosphates from aluminum hydroxide precipitation and thus a risk to cause hypophosphatemia and osteomalacia (mainly in the case of a low phosphorus diet). Aluminum can partially absorbed and accumulate, especially in cases of renal insufficiency, and in dialysed patients in particular. The symptoms of accumulation are: encephalopathy, dementia, osteomalacia, microcytic anemia.
Lidocaine can sometimes accumulate in patients suffering from advanced cirrhosis. A slight feeling of numbness of the mouth and tongue can occur if the liquid to keep long in the mouth. To help prevent the patient will quickly swallow the suspension, and he may in his mouth without any water to swallow the rinse.
Rare hypersensitivity reactions, in the form of skin rash and glossitis were described with antacids.
Acute overdose was not documented. Gastric lavage and gastric emptying were any problems to solve. A chronic excessive use may lead to a reduction of the fosfatemie and also reduce the absorption of fluoride (which entails a secondary calciumresorptie from the bones and to increased urinary secretion, which is a demineralization may result). The poisoning by aluminum were observed in patients with renal failure manifested by speech disorders, apraxia, and progressive dementia myocloniën.
An overdose of lidocaine, the following symptoms: nervousness, agitation, tremors, convulsions, respiratory depression, coma, bradycardia, low blood pressure, cardiac arrest.
other medicines should be an interval of two hours for the intake of Syngel express respect so that their absorption by the intestine not disturbed. This applies to the use of H2 antagonists and also in the use of tetracyclines. Changes in the absorption pattern of chlorpromazine, levodopa, isoniazid, indomethacin, nitro-furantoïnen, Dicoumarol, fluoro-quinolones, allopurinol, alendronate and etidronate were described by simultaneous intake of antacids. Aluminum, the bioavailability of iron, fluorine and digoxin reduced.
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This is a medecine available without a prescription.. Do not use long without medical advice. Read the instructions carefully. Keep this medicine out of the reach of children. Keep the manual as it contains important information. Ask for advice from your doctor or pharmacist. Consult your doctor if adverse reactions.